Product Description

E-Selectin Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS60008-50, BS60008-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Selectins, also designated CD62 antigens, comprise a family of carbohydrate- binding proteins involved in mediating cellμlar interactions with leukocytes. L-Selectin (also designated LECAM-1 or CD62L) is expressed on the majority of B and naive T cells and on most monocytes, neutrophils and eosinophils. L-Selectin interacts with specific carbohydrates expressed by activated endothelial cells. P-Selectin (also designated GMP-140 or CD62P), expressed on activated platelets and endothelial cells, and E-Selectin (also designated ELMA-1 or CD62E), expressed on endothelial cells, exhibit overlapping ligand specificities. E-Selectin is expressed by cytokine-stimμlated endothelial cells and is thought to be responsible for the accumμlation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascμlar lining.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: CD62 antigen-like family member E, Endothelial leukocyte adhesion molecμle 1, ELAM-1, Leukocyte-endothelial cell adhesion molecμle 2, LECAM2, CD62E, SELE, ELAM1

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide corresponding to residues in Human E-Selectin.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: E-Selectin polyclonal antibody detects endogenous levels of E-Selectin protein.

Molecular Weight: ~ 67 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P16581

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only