E-Selectin rabbit pAb - ES8463

E-Selectin rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES8463-50, ES8463-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis. [provided by RefSeq, Jul 2008],

Alternate Name: selectin E

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: IHC-p: 100-300.WB 1:500-2000, ELISA 1:10000-20000

Reactivity: Human; Rat; Mouse;

Immunogen: The antiserum was produced against synthesized peptide derived from the N-terminal region of human SELE. AA range:100-150

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 66kD

Human Gene ID: 6401

Human SWISS Prot NO: P16581

Subcellular Location: Cell membrane; Single-pass type I membrane protein.

Research Use Only