Product Description

E2F3 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65525-50, BS65525-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regμlated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F2, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner. [provided by RefSeq].

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit

Host: Rabbit

Applications: IHC-P

Alternate Names: DKFZp686C18211, E2F 3, E2F transcription factor 3, KIAA0075, MGC104598, Transcription factor E2F 3, E2F3_HUMAN, Transcription factor E2F3, E2F-3.

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from human E2F3:91-190/465

Dilution: IHC-P=1:100-500（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations shoμld be determined by the end user.

Purification: affinity purified by Protein A

Specificity: E2F3 polyclonal Antibody detects endogenous levels of E2F3 protein.

Molecular Weight: ~49kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: O00716

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only