EAAT2 Polyclonal Antibody - RA24399

EAAT2 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA24399-50, RA24399-100

Citations, Manuals and MSDS Available upon request.

Background: solute carrier family 1 member 2 (SLC1A2) Homo sapiens This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Sep 2010],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:1000-2000

Alternative Names: Excitatory amino acid transporter 2 (Glutamate/aspartate transporter II) (Sodium-dependent glutamate/aspartate transporter 2) (Solute carrier family 1 member 2)

Applications: WB

Species Cross-Reactivity: Human; Rat; Mouse

GeneID (Human): 6506

Protein MW (KDa): 62

SWISS: P43004

Source: Rabbit

Research Use Only