Product Description

EAF2 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS8722-50, BS8722-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: EAF1 and EAF2 can form a complex with ELL that targets the ternary elongation complex of Pol II, stimμlating the rate of elongation. In addition, EAF1 and EAF2 are important for the stability of the NuA4 histone acetyltransferase complex, which transcriptionally activates certain genes by acetylation of Histones H4 and H2A. Both EAF1 and EAF2 are ubiquitously expressed members of the EAF family that colocalize with ELL to the the Cajal bodies and nuclear speckles. EAF1 contains a C-terminal region rich in aspartic acid, glutamic acid and serine residues. EAF2 is an androgen-response gene and can act as a potent apoptosis inducer.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IF

Alternate Names: ELL-associated factor 2, Testosterone-regμlated apoptosis inducer and tumor suppressor protein, EAF2, TRAITS, BM-040

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fμll length Human EAF2.

Dilution: WB: 1:500~1:2000
IF: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: EAF2 polyclonal antibody detects endogenous levels of EAF2 protein.

Molecular Weight: ~ 35 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q96CJ1

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only