EBP Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A14845-20, A14845-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene is an integral membrane protein of the endoplasmic reticulum. It is a high affinity binding protein for the antiischemic phenylalkylamine Ca2+ antagonist [3H]emopamil and the photoaffinity label [3H]azidopamil. It is similar to sigma receptors and may be a member of a superfamily of high affinity drug-binding proteins in the endoplasmic reticulum of different tissues. This protein shares structural features with bacterial and eukaryontic drug transporting proteins. It has four putative transmembrane segments and contains two conserved glutamate residues which may be involved in the transport of cationic amphiphilics. Another prominent feature of this protein is its high content of aromatic amino acid residues (>23%) in its transmembrane segments. These aromatic amino acid residues have been suggested to be involved in the drug transport by the P-glycoprotein. Mutations in this gene cause Chondrodysplasia punctata 2 (CDPX2; also known as Conradi-Hunermann syndrome).
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Mouse, Rat
Protein Weight: 26kDa
Observed Molecular Weight: 26kDa
Immunogen: Synthetic peptide
Species: Human
GeneID: 10682
SWISS: Q15125
Alternate Names: CPX; CHO2; CPXD; MEND; CDPX2; EBP
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Tumor biomarkers, Signal Transduction, Kinase, Tyrosine kinases, Endocrine Metabolism, Lipid Metabolism, Cholesterol Metabolism, Drug metabolism, Cardiovascular, Lipids.
NCBI Alias: EBP
Research Use Only