Product Description

Ecat1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65765-50, BS65765-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: ECAT1 (ES cell-associated transcript 1 protein) is a 217 amino acid protein that belongs to the KHDC1 family. The ECAT1 protein contains an atypical KH domain with amino acid changes at critical sites, suggesting that it may not bind RNA. Expression of ECAT1 appears to be maximal in germinal vesicle oocytes, it tails off through metaphase II oocytes and is undetectable following the completion of the oocyte to embryo transition. Specifically expressed in the oocytes, recent studies suggest that ECAT1 may function as a regμlator of genomic imprinting in the oocyte. Defects in ECAT1 are the cause of hydatidiform mole recurrent type 2 (HYDM2), a disorder characterized by excessive trophoblast development that produces a growing mass of tissue inside the uterus at the beginning of a pregnancy. HYDM2 leads to abnormal pregnancies with no embryo, and cystic degeneration of the chorionic villi.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: IHC-P

Alternate Names: C6orf221, Chromosome 6 open reading frame 221, ES cell-associated transcript 1 protein, HYDM2, KHD3L_HUMAN, KHDC3-like protein, KHDC3L.聽

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from human Ecat1:1-100/217

Dilution: IHC-P=1:100-500

Purification: affinity purified by Protein A

Specificity: Ecat1 Polyclonal Antibody detects endogenous levels of Ecat1 protein.

Molecular Weight: 24kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q587J8

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only