ECH1 Polyclonal Antibody - E-AB-18979

ECH1 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-18979-60, E-AB-18979-120, E-AB-18979-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: ECH1

Target Synonym: 4)-dienoyl-CoA isomerase; 5)-Delta(2; Delta(3 5) Delta(2 4) dienoyl CoA isomerase; Delta(3 5) Delta(2 4) dienoyl CoA isomerase mitochondrial; Delta(3; Delta3 5 delta2 4 dienoyl CoA isomerase; Dienoyl CoA isomerase; ECH 1; Ech1; ECH1; Enoyl Coenzyme A hydratase 1; Enoyl Coenzyme A hydratase 1 peroxisomal; HPXEL; mitochondrial; MS1034; Peroxisomal enoyl CoA hydratase 1; Peroxisomal enoyl coenzyme A hydratase like protein

Research Areas: Cancer, Cardiovascular, Metabolism, Signal transduction, Tags and Cell markers

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Rat

Application: WB, IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q13011

Background: This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans, 5-cis-dienoyl-CoA to 2-trans, 4-trans-dienoyl-CoA, indicating that it is a delta3, 5-delta2, 4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators.

Concentration: 0.6 mg/mL

Immunogen: Fusion protein of human ECH1

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000

Calculated MW: 36 kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only