EDA rabbit pAb - ES8383

EDA rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES8383-50, ES8383-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Alternate Name: EDA; ED1; EDA2; Ectodysplasin-A; Ectodermal dysplasia protein; EDA protein

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Mouse

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human EDA. AA range:120-170

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 42kD

Human Gene ID: 1896

Human SWISS Prot NO: Q92838

Subcellular Location: Cell membrane; Single-pass type II membrane protein.; [Ectodysplasin-A, secreted form]: Secreted.

Research Use Only