EDEM1 Polyclonal Antibody - BT-AP15369

EDEM1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP15369-20, BT-AP15369-50, BT-AP15369-100

Citations, Manuals and MSDS Available upon request.

Background: Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. It lacks mannosidase activity.,Belongs to the glycosyl hydrolase 47 family.,subunit:Interacts with DERL2 and DERL3.,

Research Areas: Signal transduction

Target Protein: EDEM1

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: ER degradation-enhancing alpha-mannosidase-like 1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q92611; Mouse: Q925U4

Synonyms: ER degradation-enhancing alpha-mannosidase-like 1

GeneID: Human: 9695

Research Use Only