EEA1 Polyclonal Antibody - RA24432

EEA1 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA24432-50, RA24432-100

Citations, Manuals and MSDS Available upon request.

Background: disease:Antibodies against EEA1 are found in sera from patients with subacute cutaneous lupus erythematosus and other autoimmune diseases.,domain:The FYVE-type zinc finger domain mediates interactions with phosphatidylinositol 3-phosphate.,function:Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking.,similarity:Contains 1 C2H2-type zinc finger.,similarity:Contains 1 FYVE-type zinc finger.,subunit:Homodimer. Binds STX6. Binds RAB5A, RAB5B, RAB5C and RAB22A that have been activated by GTP-binding.,

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Alternative Names: EEA1; ZFYVE2; Early endosome antigen 1; Endosome-associated protein p162; Zinc finger FYVE domain-containing protein 2

Applications: WB; ELISA

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 8411

Protein MW (KDa): 162

SWISS: Q15075

Source: Rabbit

Research Use Only