EEA1 rabbit pAb - ES3758

EEA1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES3758-50, ES3758-100

Citations, Manuals and MSDS Available upon request.

Background: disease:Antibodies against EEA1 are found in sera from patients with subacute cutaneous lupus erythematosus and other autoimmune diseases., domain:The FYVE-type zinc finger domain mediates interactions with phosphatidylinositol 3-phosphate., function:Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking., similarity:Contains 1 C2H2-type zinc finger., similarity:Contains 1 FYVE-type zinc finger., subunit:Homodimer. Binds STX6. Binds RAB5A, RAB5B, RAB5C and RAB22A that have been activated by GTP-binding.,

Alternate Name: EEA1; ZFYVE2; Early endosome antigen 1; Endosome-associated protein p162; Zinc finger FYVE domain-containing protein 2

Source: Rabbit

Applications: WB; ELISA

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Mouse

Immunogen: The antiserum was produced against synthesized peptide derived from human EEA1. AA range:205-254

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 162kD

Human Gene ID: 8411

Human SWISS Prot NO: Q15075

Subcellular Location: Cytoplasm. Early endosome membrane; Peripheral membrane protein.

Research Use Only