Product Description

EFNA2 (Ephrin A2) Mouse Monoclonal Antibody

Sizes: 25μl, 100μl

Catalogue Numbers: MB4046-25, MB4046-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Ephrin-A2 also known as EFNA2 or EPH-related receptor tyrosine kinase ligand 6, is a member of the ephrin family. The Eph family receptor interacting proteins (ephrins) are a family of proteins that serve as the ligands of the Eph receptor, which compose the largest known subfamily of receptor protein-tyrosine kinases (RTKs). Ephrin-A2 and their Eph family of receptor tyrosine kinases are expressed by cells of the SVZ. Eph/ephrin interactions are implicated in axon guidance, neural crest cell migration, establishment of segmental boundaries, and formation of angiogenic capillary plexi. Ephrin subclasses are further distinguished by their mode of attachment to the plasma membrane: ephrin-A ligands bind EphA receptors and are anchored to the plasma membrane via a glycosylphosphatidylinositol (GPI) linkage, whereas ephrin-B ligands bind EphB receptors and are anchored via a transmembrane domain. Ephrin-A2 regμlates the position-specific affinity of limb mesenchyme and is involved in cartilage pattern formation in the limb.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Mouse

Applications: FC, IF, WB

Alternate Names: Ephrin-A2, EPH-related receptor tyrosine kinase ligand 6 (LERK-6), HEK7 ligand (HEK7-L), EFNA2, EPLG6, LERK6, 9606 NCBI, Homo sapiens (Human)

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: Fμll length human recombinant protein of human EFNA2 (NP_001396) produced in HEK293T cell.

Dilution: WB 1:2000, IF 1:100, FLOW 1:100

Purification: The antibody was affinity-purified from mouse ascites fluids or tissue cμlture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: IgG2b

Molecular Weight: ~ 25 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: O43921

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only