Product Description

EG5 Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB66477-50, MB66477-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Eg5 (also called kinesin-like protein 11 or Kif11) belongs to the kinesin-like family of motor proteins important in chromosome positioning, centrosome separation, and mitotic spindle formation. Phosphorylation of Eg5 by mitotic kinases regμlates its activity by modμlating its association with microtubμles. Because anti-mitotic chemotherapeutic drugs, such as taxanes, target microtubμles and have pleiotropic and sometimes toxic effects, drugs that target microtubμle-associated proteins such as Eg5 are currently in development .

Category: Primary Antibody

Reactivity: Human

Host: Mouse

Applications: WB, IF/ICC, IP

Alternate Names: EG5, KNSL1, TRIP5, Kinesin-like protein KIF11, Kinesin-like protein 1, Kinesin-like spindle protein HKSP, Kinesin-related motor protein Eg5, Thyroid receptor-interacting protein 5, TR-interacting protein 5, TRIP-5

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Purified recombinant human Eg5 protein fragments expressed in E.coli.

Dilution: WB (1/500 - 1/1000), IF/ICC (1/50 - 1/100), IP (1/10 - 1/50)

Purification: The antibody was purified by immunogen affinity chromatography.

Specificity: Recognizes endogenous levels of EG5 protein.

Molecular Weight: ~ 110 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P52732

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Research Use Only