EGF Receptor (Phospho-Tyr1045) Rabbit Polyclonal Antibody - BT-AP09479

EGF Receptor (Phospho-Tyr1045) Rabbit Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP09479-20, BT-AP09479-50, BT-AP09479-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

Research Areas: Cancer; Cell biology; Microbiology; Signal transduction; Epigenetics and nuclear signaling

Target Protein: EGFR

Applications: WB

Reactivity: Human, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: EGF Receptor

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P00533; Mouse: Q01279

Synonyms: EGF Receptor;Tyr1045; Epidermal growth factor receptor; EC 2.7.10.1; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1

GeneID: Human: 1956; Mouse: 13649

Research Use Only