Product Description

EGFR (3A9) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB3226-50, MB3226-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: P00533

Host: Mouse

Reactivity: Human

Applications: WB, IHC-F, IHC-P, ICC/IF

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200

Background: EGFR is a receptor tyrosine kinase. Receptor for epidermal growth factor (EGF) and related growth factors including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. . A single-pass transmembrane tyrosine kinase. Ligand binding to this receptor results in receptor dimerization, autophosphorylation (in trans), activation of various downstream signaling molecules and lysosomal degradation.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG1

Bioworld Molecular Weight: Calculated MW: 134 kDa; Observed MW: 170 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunofluorescence analysis of EGFR in Hela using EGFR antibody and DAPI., Western blot analysis of EGFR in Hela lysates using EGFR antibody, Western blot analysis of EGFR in Hela, A549 lysates using EGFR antibody, Immunohistochemistry analysis of paraffin-embedded Human breast cancer tissue using EGFR antibody High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Alternative Name: EGFR; ERBB; ERBB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1

Immunogen: Synthetic Peptide of EGFR

Conjugate: Unconjugated

Modification: Unmodified