Product Description

EGFR (5E9) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB3203-50, MB3203-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: P00533

Host: Mouse

Reactivity: Human

Applications: WB, IP,

All Applications: WB: 1/500-1/1000 IP: 1/20

Background: EGFR is a receptor tyrosine kinase. Receptor for epidermal growth factor (EGF) and related growth factors including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. . A single-pass transmembrane tyrosine kinase. Ligand binding to this receptor results in receptor dimerization, autophosphorylation (in trans), activation of various downstream signaling molecules and lysosomal degradation.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG1

Bioworld Molecular Weight: Calculated MW: 134 kDa; Observed MW: 170 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of EGFR in A431, Hela lysates using EGFR antibody., Immunoprecipitation analysis of EGFR in Hela lysates using EGFR antibody, Western blot analysis of EGFR in EGF Receptor/ErbB1 in Hela lysates using EGF Receptor/ErbB1 antibody.

Alternative Name: EGFR; ERBB; ERBB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1

Immunogen: Synthetic Peptide of EGFR

Conjugate: Unconjugated

Modification: Unmodified