EGFR Monoclonal Antibody (M6) - BT-MCA0468

EGFR Monoclonal Antibody (M6)

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-MCA0468-20, BT-MCA0468-50, BT-MCA0468-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

Research Areas: Signal transduction; Cancer; Microbiology

Target Protein: EGFR

Applications: WB

Reactivity: Human

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Epidermal growth factor receptor

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 134277

UniProt Accession: Human: P00533; Mouse: Q01279

Synonyms: EGFR; ERBB; ERBB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1

GeneID: Human: 1956; Mouse: 13649

Research Use Only