Product Description

EGFR Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB10360-50, MB10360-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P00533

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, ICC/IF, IP,

All Applications: WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20

Background: EGFR is a receptor tyrosine kinase. Receptor for epidermal growth factor (EGF) and related growth factors including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. . A single-pass transmembrane tyrosine kinase. Ligand binding to this receptor results in receptor dimerization, autophosphorylation (in trans), activation of various downstream signaling molecules and lysosomal degradation.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 134 kDa; Observed MW: 175 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of EGFR in mouse liver lysates using EGFR antibody., Western blot analysis of EGFR in Hela lysates using EGFR antibody., Immunocytochemistry analysis of EGFR in Hela using EGFR antibody, and DAPI

Alternative Name: EGFR; ERBB; ERBB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1

Immunogen: A synthetic peptide of human EGFR

Conjugate: Unconjugated

Modification: Unmodified