EGLN1/EGLN2 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A10342-20, A10342-100
Citations, Manuals and MSDS Available upon request.
Background: The proteins encoded by EGLN1/EGLN2 gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human
Protein Weight: 36kDa/43kDa/46kDa/40kDa
Observed Molecular Weight: 44kDa
Immunogen: Synthetic peptide
Species: Human
GeneID: 54583/112398
SWISS: Q9GZT9/Q96KS0
Alternate Names: EGLN1/EGLN2
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
NCBI Alias: EGLN1/EGLN2
Research Use Only