eIF2α Mouse Monoclonal Antibody - RA11133

eIF2α Mouse Monoclonal Antibody

Size: 50μL, 100μL

Catalogue Numbers: RA11133-50, RA11133-100

Citations, Manuals and MSDS Available upon request.

Background: eukaryotic translation initiation factor 2 subunit alpha (EIF2S1) Homo sapiens The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161) . The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]) .[supplied by OMIM, Feb 2010],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Applications: WB; IF/ICC; IP

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 1965

Protein MW (KDa): 38

SWISS: P05198

Source: Mouse

Research Use Only