eIF4A1 Mouse mAb - EM1136

eIF4A1 Mouse mAb

Sizes: 50μL, 100μL

Catalogue Numbers: EM1136-50, EM1136-100

Citations, Manuals and MSDS Available upon request.

Background: The eukaryotic initiation factor-4A (eIF4A) family consists of 3 closely related proteins EIF4A1, EIF4A2, and EIF4A3. These factors are required for the binding of mRNA to 40S ribosomal subunits. Eukaryotic initiation factor (eIF) complex 2 forms a ternary complex with GTP and the initiator Met-tRNA – this process is regulated by guanine nucleotide exchange and phosphorylation and serves as the main regulatory element of the bottleneck of protein expression.

Alternate Name: DDX2, eIF 4A I, Eukaryotic initiation factor 4A-1, ATP-dependent RNA helicase eIF4A-1, DDX2A

Source: Mouse

Applications: WB, IHC, IF

Dilution: WB 1:1, 000-3, 000 IF 1:100-200  IHC 1:100-200

Reactivity: Human, Rat, Mouse

Immunogen: Synthetic Peptide

Storage and Stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality: Monoclonal

Isotype: IgG1

Concentration: 1mg/mL

Observed Band (KD): 48kDa

Human Gene ID: 1973

Human SWISS Prot NO: P60842

Subcellular Location: Cytosol, Extracellular region or secreted

Research Use Only