eIF4B (phospho Ser422) rabbit pAb - ES5967

eIF4B (phospho Ser422) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES5967-50, ES5967-100

Citations, Manuals and MSDS Available upon request.

Background: function:Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F., similarity:Contains 1 RRM (RNA recognition motif) domain., subunit:Self-associates and interacts with EIF3 p170 subunit.,

Alternate Name: EIF4B; Eukaryotic translation initiation factor 4B; eIF-4B

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.

Reactivity: Human; Mouse

Immunogen: The antiserum was produced against synthesized peptide derived from human eIF4B around the phosphorylation site of Ser422. AA range:388-437

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 80kD

Human Gene ID: 3716

Human SWISS Prot NO: P23588

Subcellular Location: cytosol, polysome, eukaryotic translation initiation factor 4F complex, dendrite, neuronal cell body,

Research Use Only