eIF4E Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA24492-50, RA24492-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: eukaryotic translation initiation factor 4E (EIF4E) Homo sapiens The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015], Reactivity: Human, Mouse, Rat, Monkey Host: Rabbit Applications: WB, IHC-p, IF (paraffin section), ELISA Alternate Names: EIF4E, EIF4EL1, EIF4F, Eukaryotic translation initiation factor 4E, eIF-4E, eIF4E, eIF-4F 25 kDa subunit, mRNA cap-binding protein Clonality: Polyclonal Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. Molecular Weight: 25 Protein Molecular Weight (kDa): 25 Storage: -20°C/1 year Human Gene ID: 1977 Human SwissProt Number: P06730 Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Research Use Only