eIF4G (phospho-Ser1108) Rabbit Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA24495-50, RA24495-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: eukaryotic translation initiation factor 4 gamma 1 (EIF4G1) Homo sapiens The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly (A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. [provided by RefSeq, Aug 2010], Reactivity: Human, Mouse, Rat Host: Rabbit Applications: WB Alternate Names: Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1) (p220) Clonality: Polyclonal Dilution: WB 1:1000-2000 Molecular Weight: 180 Protein Molecular Weight (kDa): 180 Storage: -20°C/1 year Human Gene ID: 1981 Human SwissProt Number: Q04637 Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Research Use Only