eIF4G (phospho Ser1148) rabbit pAb - ES5084

eIF4G (phospho Ser1148) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES5084-50, ES5084-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly (A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. [provided by RefSeq, Aug 2010],

Alternate Name: EIF4G1; EIF4F; EIF4G; EIF4GI; Eukaryotic translation initiation factor 4 gamma 1; eIF-4-gamma 1; eIF-4G 1; eIF-4G1; p220

Source: Rabbit

Applications: IHC; IF; ELISA

Dilution: WB 1:500-2000, Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human eIF4G around the phosphorylation site of Ser1108. AA range:1074-1123

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 1981

Human SWISS Prot NO: Q04637

Subcellular Location: Cytoplasm, Stress granule.

Research Use Only