Product Description

eIF5A Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB10470-50, MB10470-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P63241

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-P, IP,

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20

Background: mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, functions as a regulator of p53/TP53 and p53/TP53-dependent apoptosis. Regulates also TNF-alpha-mediated apoptosis.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 17 kDa; Observed MW: 17 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of eIF5A in Jurkat lysates using eIF5A antibody., Western blot analysis of eIF5A in Jurkat, THP-1, C6, 3T3, Hela lysates using eIF5A antibody., Immunohistochemistry analysis of paraffin-embedded Human breast cancer using eIF5A antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Alternative Name: EIF-5A; EIF5A1; eIF5AI; Eukaryotic initiation factor 5A

Immunogen: A synthetic peptide of human eIF5A

Conjugate: Unconjugated

Modification: Unmodified