Product Description

EIF6 (Phospho-Ser235) Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA36839-50, RA36839-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: eukaryotic translation initiation factor 6 (EIF6) Homo sapiens Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple non-protein coding transcript variants and variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2012],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Eukaryotic translation initiation factor 6 (eIF-6) (B (2)GCN homolog) (B4 integrin interactor) (CAB) (p27 (BBP))

Clonality: Polyclonal

Dilution: WB 1:500-2000

Storage: -20°C/1 year

Human Gene ID: 3692

Human SwissProt Number: P56537

Condition: Liquid in PBS containing 50% glycerol, and 0.155% sodium azide.

Research Use Only