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View abinScience ELISA, antibody, protein collection

Elezanumab ELISA Kit - DV303018

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Elezanumab ELISA Kit

Size: 96T

Catalogue Number: DV303018-96

Citations, Manuals and MSDS Available upon request.

Stability and Storage: The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.

Detection Method: Colorimetric

Sample Type: Plasma, Serum

Assay Type: Quantitative

Sensitivity: 0.156 μg/ml

Range: 0.31-5 μg/mL

Recovery: 80-120%

Background: Elezanumab is a fully humanized monoclonal antibody directed against repulsive guidance molecule A (RGMa). Studies in patients with multiple sclerosis (MS) demonstrate RGMa upregulation, which inhibits axonal growth and myelination, oligodendroglial regeneration and functional recovery after trauma or inflammation. Elezanumab treatment promoted axon regeneration, neuroprotection, remyelination, and immune modulation in several MS-relevant preclinical models. Elezanumab was previously well-tolerated as a single dose to healthy volunteers.

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For Research Use Only.