Product Description

ELL Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA24515-50, RA24515-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: disease:A chromosomal translocation involving ELL is found in acute leukemias. Translocation t (11;19) (q23;p13.1) with MLL/HRX. The result is a rogue activator protein., function:Elongation factor that can increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the ELL/occludin family., subcellular location:Colocalizes with EAF2 to nuclear speckles. Also localized to Cajal (coiled) bodies., subunit:Interacts with EAF1 and EAF2., tissue specificity:Expressed in all tissues tested. Highest levels found in placenta, skeletal muscle, testis and peripheral blood leukocytes.,

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, IHC-p, IF (paraffin section), ELISA

Alternate Names: ELL, C19orf17, RNA polymerase II elongation factor ELL, Eleven-nineteen lysine-rich leukemia protein

Clonality: Polyclonal

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Molecular Weight: 65

Protein Molecular Weight (kDa): 65

Storage: -20°C/1 year

Human Gene ID: 8178

Human SwissProt Number: P55199

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only