Product Description

ELOC Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA32149-50, RA32149-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: transcription elongation factor B subunit 1 (TCEB1) Homo sapiens This gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been identified. [provided by RefSeq, Mar 2011],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 12

Protein Molecular Weight (kDa): 12

Storage: -20°C/1 year

Human Gene ID: 6921

Human SwissProt Number: Q15369

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only