EMC8 Polyclonal Antibody - E-AB-10253

EMC8 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-10253-60, E-AB-10253-120, E-AB-10253-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: EMC8

Target Synonym: C16orf2; C16orf4; COX4 neighbor; COX4; neighbor of; COX4AL; Cox4nb; CX4NB; ER membrane protein complex subunit 8; FAM158B; family with sequence similarity 158; member B; Neighbor of COX4; NOC4; Protein FAM158B

Research Areas: Cell Biology

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB, IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: O43402

Background: COX4NB (Neighbor of COX4) is a 210 amino acid protein encoded by the human gene COX4NB. COX4NB belongs to the UPF0172 (NOC4) family and is found on chromosome 16, adjacent to the gene that encodes COX4. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16 through the CREBBP gene which encodes a critical CREB binding protein. Crohn’s disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. An association with systemic lupus erythematosis and a number of other auto-immune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier.

Concentration: 0.4 mg/mL

Immunogen: Recombinant protein of human EMC8

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Calculated MW: 24kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only