Product Description

EMMPRIN (Q370) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS2472-50, BS2472-100

Sizes: 50µl, 100µl

Swiss-Prot: P35613

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

Background: Extracellular matrix metalloproteinase inducer (EMMPRIN), also designated basigin or CD147, is involved in the regulation of matrix remodeling at the epidermal-dermal interface. EMMPRIN stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes, which are typically increased during tissue degradation and wound healing, are important factors in cancer invasion and metastasis.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: EMMPRIN (Q370) polyclonal antibody detects endogenous levels of EMMPRIN protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of EMMPRIN (Q370) polyclonal antibody at 1:500 dillution
Lane 1: HEK293T whole cell lysate
Lane 2: DLD whole cell lysate
Lane 3: The fetal heart tissue lysate of Mouse
Lane 4: The fetal heart tissue lysate of Rat, Immunohistochemistry (IHC) analyzes of EMMPRIN (Q370) pAb in paraffin-embedded human colorectal carcinoma tissue at 1:50.

Bioworld Molecular Weight: ~ 42 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: Basigin; 5F7; Collagenase stimulatory factor; Extracellular matrix metalloproteinase inducer; EMMPRIN; Leukocyte activation antigen M6; OK blood group antigen; Tumor cell-derived collagenase stimulatory factor; TCSF; CD147; BSG;

Immunogen: Synthetic peptide, corresponding to amino acids 350-400 of Human EMMPRIN.

Conjugate: Unconjugated

Modification: Unmodified