Product Description

EMR3 (Y652) Polyclonal Antibody

Catalogue Numbers: BS2595-50, BS2595-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q9BY15

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB IHC IF

All Applications: WB: 1:500~1:1000
IHC: 1:50~1:200
IF: 1:50~1:200

Background: EMR3 is a member of the class B seven-span transmembrane (TM7) receptor family expressed predominantly by cells of the immune system. Family members are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor (EGF)-like domains coupled to a TM7 domain via a mucin-like spacer domain. This gene is closely linked to the gene encoding egf-like molecule containing mucin-like hormone receptor 2 on chromosome 19. This protein may play a role in myeloid-myeloid interactions during immune and inflammatory responses. Alternative splicing of this gene results in two transcript variants encoding two distinct isoforms.EMR3 has been reported to be expressed in neutrophils, monocytes, and macrophages. ESTs have been isolated from liver/spleen and mixed libraries.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: EMR3 (Y652) polyclonal antibody detects endogenous levels of EMR3 protein.

Extra Notes: Western blot (WB) analysis of EMR3 (Y652) pAb at 1:500 dilution
Lane1:H9C2 whole cell lysate(40ug)
Lane2:CT26 whole cell lysate(40ug)
Lane3:HepG2 whole cell lysate(40ug)
Lane4:MCF-7 whole cell lysate(40ug)
Lane5:K562 whole cell lysate(40ug)

Bioworld Molecular Weight: ~ 70 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: EGF-like module-containing mucin-like hormone receptor-like 3; EGF-like module receptor 3; UNQ683/PRO1562; EMR3

Immunogen: Synthetic peptide, corresponding to amino acids 620-671 of Human EMR3.

Conjugate: Unconjugated

Modification: Unmodified