Endo180 (G145) Polyclonal Antibody-BS2506

Endo180 (G145) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS2506-50, BS2506-100

Sizes: 50µl, 100µl

Swiss-Prot: Q9UBG0

Host: Rabbit

Reactivity: Human

Applications: WB, IHC

Background: Endo180 (Endocytic receptor 180), also known as macrophage mannose receptor C type 2 (MRC2), urokinase plasminogen activator receptor-associated protein (uPARAP) or CD280 antigen, is a ubiquitously expressed, type I membrane protein with predominant expression in fetal lung and kidney. The extracellular domain of Endo180 contains a fibronectin type II domain, eight C-type lectin domains and a cysteine-rich domain. Endo180 functions as a cell surface receptor and mediates collagen matrix remodeling as well as cell migration by playing a role in the uptake and lysosomal degradation of collagen.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Endo180 (G145) polyclonal antibody detects endogenous levels of Endo180 protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of Endo180 (G145) pAb at 1:500 dilution
Lane 1: A549 whole cell lysate (40ug)
Lane 2: Panc1 whole cell lysate (40ug)
Lane 3: U-87MG whole cell lysate (40ug), Immunohistochemistry (IHC) analyzes of Endo180 (G145) pAb in paraffin-embedded human tonsil carcinoma tissue at 1:50.

Bioworld Molecular Weight: ~ 167 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: C-type mannose receptor 2; C-type lectin domain family 13 member E; Endocytic receptor 180; Macrophage mannose receptor 2; Urokinase-type plasminogen activator receptor-associated protein; UPAR-associated protein; Urokinase receptor-associated protein; CD280; MRC2; CLEC13E; ENDO180; KIAA0709; UPARAP

Immunogen: Synthetic peptide, corresponding to amino acids 114-160 of Human Endo180.

Conjugate: Unconjugated

Modification: Unmodified