Product Description

Endophilin I Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS7108-50, BS7108-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The Endophilins comprise a family of three SH3 domain-containing proteins designated Endophilin I, II and III, or alternatively known as SH3P4, SH3P8 and SH3P13, respectively. These proteins associate with amphiphysin, synaptojanin and dynamin and are implicated in presynaptic vesicle trafficking at nerve terminals. The expression patterns of the Endophilins are consistent with their cellμlar functions at the neuronal synapse as Endophilin I is expressed only in the brain. Both Endophilin II and Endophilin III are detected in a variety of tissues. Endophilin I is also implicated in modμlating G proteincoupled receptor signaling by functioning as an adapter protein and directing β1 adrenergic receptors to the endocytic machinery.

Category: Primary Antibody

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, IF

Alternate Names: Endophilin-A1, EEN-B1, Endophilin-1, SH3 domain protein 2A, SH3 domain-containing GRB2-like protein 2, SH3GL2, CNSA2, SH3D2A

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fμll length Human Endophilin I.

Dilution: WB: 1:500~1:2000
IF: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Endophilin I polyclonal antibody detects endogenous levels of Endophilin I protein.

Molecular Weight: ~ 40 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q99962

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only