Product Description

eNOS (2E8) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB3213-50, MB3213-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: P29474

Host: Mouse

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1/500-1/1000

Background: Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.Isoform eNOS13C: Lacks eNOS activity, dominant-negative form that may down-regulate eNOS activity by forming heterodimers with isoform 1.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of eNOS in rat Heart, huvec , JurkatLysates using eNOS antibody.

Bioworld Molecular Weight: Calculated MW: 133 kDa; Observed MW: 133 kDa

Specificity: IgG1

Alternative Name: NOS3; Nitric oxide synthase; endothelial; Constitutive NOS; cNOS; EC-NOS; Endothelial NOS; eNOS; NOS type III; NOSIII

Immunogen: Recombinant Protein of eNOS

Conjugate: Unconjugated

Modification: Unmodified