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ENPP2 Rabbit pAb - A2522

ENPP2 Rabbit pAb - A2522

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ENPP2 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A2522-20, A2522-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified.

Category: Polyclonal Antibodies

Applications: WB, ELISA

Cross-reactivity: Human, Mouse

Protein Weight: 99kDa

Observed Molecular Weight: 110-115kDa

Immunogen: Recombinant protein (or fragment) .

Species: Human

GeneID: 5168

SWISS: Q13822

Alternate Names: ATX; NPP2; ATX-X; PDNP2; LysoPLD; AUTOTAXIN; PD-IALPHA; ENPP2

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Cancer, Tumor biomarkers, Signal Transduction, Endocrine Metabolism, Lipid Metabolism, Lipases, Neuroscience, Neurodegenerative Diseases, Cardiovascular, Angiogenesis, Heart, Lipids, Cardiovascular diseases, Heart disease.

NCBI Alias: ENPP2

Research Use Only