ENPP3 Polyclonal Antibody
Catalogue Numbers: BS60438-50, BS60438-100
Sizes: 50µl, 100µl
Alternative Name: Ectonucleotide pyrophosphatase/phosphodiesterase family member 3; E-NPP 3; ENPP 3; ENPP-3; E-NPP3; Phosphodiesterase I beta; PD-Ibeta; Phosphodiesterase I/nucleotide pyrophosphatase 3; CD203c; Alkaline phosphodiesterase I; Nucleotide pyrophosphatase; NPPase; PDNP3
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: O14638
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB
All Applications: WB: 1:500~1:1000
Background: Ecto-nucleotide pyrophosphatase/phospho-diesterase-I enzymes (E-NPP), a group of type II transmembrane proteins, cleave phosphodiester and phosphosulfate bonds in deoxynucleotides, NAD, and nucleotide sugars. There exist three closely related proteins in mammalian species: E-NPP1 (PC-1), E-NPP2 (PDNP2), and E-NPP-3, also known as CD203c, each expressed in different cells or at different locations in the same cells. Basophils, a type of major proinflammatory effector cells involved in diverse pathologic reactions, exhibit CD203c expression. For instance, CD203c expression increases in response to a variety of allergens, including cat dander, latex, and bee and wasp venom. Hovever, these allergies are not the only condition associated with CD203c upregulation; CD203c upregulation may also serve as a tumor marker for colon carcinoma.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: ENPP3 polyclonal antibody detects endogenous levels of ENPP3 protein.
Bioworld Molecular Weight: ~ 100 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot (WB) analysis of ENPP3 polyclonal antibody at 1:500 dilution
Lane 1: Jurkat cell lysate
Lane 2: sp2/0 cell lysate
Lane 3: H9C2 cell lysate
Immunogen: A synthetic peptide corresponding to residues in Human ENPP3.
Conjugate: Unconjugated
Modification: Unmodified