Product Description

ENSA Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS76417-50, BS76417-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The protein encoded by this gene belongs to a highly conserved cAMP-regμlated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sμlfonylurea receptor, ABCC8/SUR1. ABCC8 is the regμlatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insμlin release from pancreatic beta cells. This protein is thought to be an endogenous regμlator of KATP channels. In vitro studies have demonstrated that this protein modμlates insμlin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes. At least eight alternatively spliced transcript variants encoding distinct isoforms have been observed.

Category: Primary Antibody

Reactivity: Mouse

Host: Rabbit

Applications: WB

Alternate Names: ENSA, ARPP-19e

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide of human ENSA(NP_996929.1).

Dilution: WB, 1:500 - 1:2000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Unmodification

Molecular Weight: 13kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: O43768

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only