Product Description

ENTK (light chain, Cleaved-Ile785) Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA24573-50, RA24573-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: catalytic activity:Activation of trypsinogen by selective cleavage of 6-Lys-|-Ile-7 bond., disease:Defects in PRSS7 are a cause of enterokinase deficiency [MIM:226200]; a life-threatening intestinal malabsorption disorder characterized by diarrhea and failure to thrive., function:Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases., PTM:The chains are derived from a single precursor that is cleaved by a trypsin-like protease., similarity:Belongs to the peptidase S1 family., similarity:Contains 1 MAM domain., similarity:Contains 1 peptidase S1 domain., similarity:Contains 1 SEA domain., similarity:Contains 1 SRCR domain., similarity:Contains 2 CUB domains., similarity:Contains 2 LDL-receptor class A domains., subunit:Heterodimer of a catalytic (light) chain and a multidomain (heavy) chain linked by a disulfide bond., tissue specificity:Intestinal brush border.,

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, ELISA

Alternate Names: Enteropeptidase (EC 3.4.21.9;Enterokinase;Serine protease 7;Transmembrane protease serine 15) [Cleaved into: Enteropeptidase non-catalytic heavy chain, Enteropeptidase catalytic light chain]

Clonality: Polyclonal

Dilution: WB 1:1000-2000 ELISA 1:5000-20000

Molecular Weight: 26

Protein Molecular Weight (kDa): 26

Storage: -20°C/1 year

Human Gene ID: 5651

Human SwissProt Number: P98073

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only