Product Description

Epac1 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB10882-50, MB10882-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: O95398

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, IP,

All Applications: WB: 1/500-1/1000 IP: 1/20

Background: The activation of RaP1 by cAMP is independent of PKA and is mediated by recently discovered family of guanine nucleotide exchange factors (GEFs) called cAMP-GEFs or Epacs. The Epac signaling therefore represents a novel mechanism for cAMP signaling with in the cAMP cascade.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 104 kDa; Observed MW: 104 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Epac1 in HepG2 lysates using Epac1 antibody., Western blot analysis of Epac1 in 3T3 lysates using Epac1 antibody.

Alternative Name: RAPGEF3; CGEF1; EPAC; EPAC1; Rap guanine nucleotide exchange factor 3; Exchange factor directly activated by cAMP 1; Exchange protein directly activated by cAMP 1; EPAC 1; Rap1 guanine-nucleotide-exchange factor directly activated by cAMP

Immunogen: A synthetic peptide of human Epac1

Conjugate: Unconjugated

Modification: Unmodified