EphA2 Monoclonal Antibody - BT-MCA4164

EphA2 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4164-50, BT-MCA4164-100

Citations, Manuals and MSDS Available upon request.

Background: EPH receptor A2 (EphA2), with 976-amino acid protein (about 107 kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EphA1, EphA2, EphA3, EphA4, EphA5, EphA6, EphA7, EphA8, EphA10, EphB1, EphB2, EphB3, EphB4 and EphB6 are Eph family receptors for Ephrin family ligands. In normal cells, EphA2 negatively regulates cell growth and invasiveness. EphA2 is overexpressed by many human cancers, and is often associated with poor prognostic features. The clinical significance of the expression of EphA2 was observed in breast, prostate, colon, skin, cervical, ovarian, and lung cancers.EphA2 may serve as a novel target for bladder cancer, colonic adenocarcinoma and ovarian cancer therapy.

Research Areas: Cardiovascular

Target Protein: EphA2

Applications: WB, IHC

Reactivity: Human

Clonality: Monoclonal

Clone ID: 1B3C7

Host: Mouse

Isotype: Mouse IgM

Full Product Name: EphA2

Immunogen: Purified recombinant fragment of EphA2 expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

UniProt Accession: P29317

Synonyms: ECK, EPHA2

GeneID: 1969

Research Use Only