EphA7 (E477) Polyclonal Antibody-BS2067

EphA7 (E477) Polyclonal Antibody

Catalogue Numbers: BS2067-50, BS2067-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q15375

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

All Applications: WB: 1:500~1:1000
IHC: 1:50~1:200

Background: EphAs are a family of receptor tyrosine kinases that are involved in axonal guidance during development. These receptors and their ligands, the ephrins, act via repulsive mechanisms to guide growing axons towards their appropriate targets and allow for the correct developmental connections to be made. Ligand binding to an Eph receptor results in tyrosine phosphorylation of the kinase domain, and repulsion of axonal growth cones and migrating cells.Three different EphA7 splice variants, a full-length form and two truncated versions lacking kinase domains, are expressed in the neural folds.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: EphA7 (E477) polyclonal antibody detects endogenous levels of EphA7 protein.

Extra Notes: Western blot (WB) analysis of EphA7 (E477) pAb at 1:500 dilution
Lane1:3T3-L1 whole cell lysate(40ug)
Lane2:H9C2 whole cell lysate(40ug)
Lane3:A549 whole cell lysate(40ug)
Lane4:HEK293T whole cell lysate(40ug)

Bioworld Molecular Weight: ~ 112 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Ephrin type-A receptor 7; Tyrosine-protein kinase receptor EHK-3; Eph-homology kinase-3; Receptor protein-tyrosine kinase HEK11

Immunogen: Synthetic peptide, corresponding to amino acids 443-495 of Human EphA7.

Conjugate: Unconjugated

Modification: Unmodified