EpoR Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA24657-50, RA24657-100
Citations, Manuals and MSDS Available upon request.
Background: erythropoietin receptor (EPOR) Homo sapiens This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Alternative Names: EPOR; Erythropoietin receptor; EPO-R
Applications: WB; IF/ICC; ELISA
Species Cross-Reactivity: Human; Mouse; Rat; Monkey
GeneID (Human): 2057
Protein MW (KDa): 65
SWISS: P19235
Source: Rabbit
Research Use Only