EPOR Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A2917-20, A2917-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.
Category: Polyclonal Antibodies
Applications: WB, IF/ICC, IF-P, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 55kDa
Observed Molecular Weight: 60kDa
Immunogen: Synthetic peptide .
Species: Human
GeneID: 2057
SWISS: P19235
Alternate Names: EPO-R; EPOR
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 IF/ICC, 1:50 - 1:200 IF-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, G protein signaling, Small G proteins, Cell Biology Developmental Biology, Apoptosis, Immunology Inflammation, Stem Cells, Hematopoietic Progenitors, Cardiovascular, Angiogenesis, Heart, Hypertrophy.
NCBI Alias: EPOR
Research Use Only