Epsin 1 rabbit pAb - ES2284

Epsin 1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES2284-50, ES2284-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the epsin protein family. The encoded protein binds clathrin and is involved in the endocytosis of clathrin-coated vesicles. Loss of function of this gene is associated with reduced tumor growth and progression in certain cancer types. [provided by RefSeq, Mar 2016],

Alternate Name: EPN1; Epsin-1; EH domain-binding mitotic phosphoprotein; EPS-15-interacting protein 1

Source: Rabbit

Applications: WB; ELISA

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized peptide derived from Epsin 1 . at AA range: 140-220

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 85kD

Human Gene ID: 29924

Human SWISS Prot NO: Q9Y6I3

Subcellular Location: Cytoplasm. Cell membrane; Peripheral membrane protein. Nucleus. Membrane, clathrin-coated pit. Associated with the cytoplasmic membrane at sites where clathrin-coated pits are forming. Colocalizes with clathrin and AP-2 in a punctate pattern on the plasma membrane. Detected in presynaptic nerve terminals and in Golgi stacks. May shuttle to the nucleus when associated with ZBTB16/ZNF145 (By similarity).

Research Use Only