ErbB-2/HER-2 Mouse mAb - EM1045

ErbB-2/HER-2 Mouse mAb

Sizes: 50μL, 100μL

Catalogue Numbers: EM1045-50, EM1045-100

Citations, Manuals and MSDS Available upon request.

Background: ErbB 2 is a receptor tyrosine kinase of the ErbB 2 family. It is closely related instructure to the epidermal growth factor receptor. ErbB 2 oncoprotein is detectable in a proportion of breast and other adenocarconomas, as well as transitional cell carcinomas. In the case of breast cancer, expression determined by immunohistochemistry has been shown to be associated with poor prognosis.

Alternate Name: CD340, HER 2/neu, HER2, MLN 19, MLN19, NEU, NGL, p185, p185erbB2, Proto oncogene c ErbB 2, Proto oncogene Neu, TKR1

Source: Mouse

Applications: WB, IHC

Dilution: WB 1:2, 000-4, 000 IHC 1:200

Reactivity: Human, Rat, Mouse

Immunogen: Synthetic Peptide

Storage and Stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality: Monoclonal

Isotype: IgG1

Concentration: 1mg/mL

Observed Band (KD): 138kDa

Human Gene ID: 2064

Human SWISS Prot NO: P04626

Subcellular Location: Cytoplasm. Nucleus and Cell membrane

Research Use Only