Product Description

ERCC1 (7F6) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB3058-50, MB3058-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: P07992

Host: Mouse

Reactivity: Human

Applications: WB

All Applications: WB: 1/500-1/1000

Background: DNA repair systems operate in all living cells to manage a variety of DNA lesions. Nucleotide excision repair (NER) is implemented in cases where bulky helix-distorting lesions occur, such as those brought about by UV and certain chemicals. Research studies have shown that expression of ERCC1 is related to survival rate and response to chemotherapeutic drugs in several human cancers including non-small cell lung cancer (NSCLC).

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of ERCC1 in T47D, ZR751, CaCO2 and Molt4Lysates using ERCC1 antibody.

Bioworld Molecular Weight: Calculated MW: 33 kDa; Observed MW: 39 kDa

Specificity: IgG2b

Alternative Name: ERCC1; DNA excision repair protein ERCC-1

Immunogen: Purified recombinant human ERCC1 protein fragments expressed in E.coli.

Conjugate: Unconjugated

Modification: Unmodified