ERCC3 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A12702-20, A12702-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes an ATP-dependent DNA helicase that functions in nucleotide excision repair. The encoded protein is a subunit of basal transcription factor 2 (TFIIH) and, therefore, also functions in class II transcription. Mutations in this gene are associated with Xeroderma pigmentosum B, Cockayne's syndrome, and trichothiodystrophy. Alternative splicing results in multiple transcript variants.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 89kDa
Observed Molecular Weight: 89kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 2071
SWISS: P19447
Alternate Names: XPB; BTF2; Ssl2; TTD2; GTF2H; RAD25; TFIIH; ERCC3
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Transcription Factors, DNA Damage Repair, Cancer, Cell Biology Developmental Biology, Apoptosis, Endocrine Metabolism, Nucleotide metabolism.
NCBI Alias: ERCC3
Research Use Only